The Windup Girl was the first book I read in 2011 and I can say that the year had started on the right foot.
The book setting is Post-Apocalyptic Bangkok, living on time borrowed from both the raising sea levels and the latest versions of food oligopolies biowarfare vectors. The world is slowly shrinking again, the initial catastrophic expansion caused by the exhaustion of the oil reserves. Nevertheless, the main sources of power still are, once more, beasts of burden and the weather.
Collapse of the economies of entire continents, chronic malnourishment, religious cleansings and an endless string of resistant terminal infections have pushed humanity to the very edge of existence. And yet, human greed and blind ambition still offer the impetus for the endless power-games that care not how many lives get trampled under its threads.
An American investor/spy after Thailand's only remaining bio-treasure; a shrewd and ruthless refugee trying to rebuilt his empire lost to murderous fundamentalism; government factions locked in a power-struggle to the death; and a seductively-designed Japanese Windup Girl that will unwillingly serve as the catalyst for the brewing explosion.
The book losses its 5th star because of its ending - and I will say no more to avoid any spoilers.